Facial palsy after administration of immune checkpoint inhibitors: case report, literature review and clinical care management

Facial palsy after administration of immune checkpoint inhibitors: case report, literature review and clinical care management

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Neurological immune-related adverse events (irAEs) due to immune checkpoint inhibitors (ICI) are rare complications of immunotherapy, particularly dreadful for patients and clinical teams.Indeed, neurological irAEs are potentially severe and their diagnosis require prompt recognition and treatment.Additionally, the spectrum of neurological irAEs is utvara hellkite price broad, affecting either neuromuscular junction, peripheral or central nervous system.

Here, we described the case of a 55-year man with metastatic melanoma, facing a brutal right peripheral cerebral palsy after his third ipilimumab/nivolumab infusion.After neutral checkered phone case the case presentation, we reviewed the literature about this rare complication of immunotherapy, and described its diagnosis work-up and clinical management.